Figure 5

Quantification of co-circularity excluding co-linearity. D_diff(r) was calculated with all bouton sites which are co-linear with the injection site excluded (30° ≥ β ≤ 150°). All cases where the true value was significantly different from controls were marked as '*'. (A) Case ts9509 had D_diff significantly different from the control case at r = 1.5, 3, 4.5, 6λ (P <0.01). The values of τ which minimized the D_diff at r = 1.5, 3, 4.5, 6λ were 30°, 50°, 60°, 60° respectively, with differences D_diff(r, 0) − D_diff(r, ${\tau }_{\text{best}}$(r)) of 5°, 32.8°, 32.5°, 47.7° respectively. (B) Case ts9514 had D_diff significantly different from the control case at r = 0, 1.5, 4.5, 6λ (P <0.02). The values of τ which minimized the D_diff at r = 1.5, 3, 4.5, 6λ were 0°, 20°, 20°, 30° respectively, with differences D_diff(r, 0) − D_diff(r, ${\tau }_{\text{best}}$(r)) of 0°, 7.1°, 21.1°, 36.4° respectively. (C) Case ts9529 had D_diff significantly different from the control case at r = 1.5, 3, 4.5λ (P <0.01). The values of τ which minimized the D_diff at r = 1.5, 3, 4.5, 6λ were 40°, 50°, 70°, 60° respectively, with differences D_diff(r, 0) − D_diff(r, ${\tau }_{\text{best}}$(r)) of 12.4°, 9.5°, 3.1°, 19.1° respectively. (D) Case ts9531 had D_diff significantly different from the control case at r = 1.5, 4.5, 6λ (P <0.02). The values of τ which minimized the D_diff at r = 1.5, 3, 4.5, 6λ were 10°, 60°, 60°, 10° respectively, with differences D_diff(r, 0) − D_diff(r, ${\tau }_{\text{best}}$(r)) of 2.0°, 3.9°, 16.0°, 11.5° respectively.