Figure 4

AMPAR-mediated EPSCs during maturation of adult-generated GCs. (A) The 10-90% rise time of AMPAR-mediated EPSCs did not differ between different stages of maturation (class 3: eleven slices, eleven mice; class 4: sixteen slices, fourteen mice; class 5: nine slices, seven mice). (B) Similar decay time constants were observed for the different classes of developing adult newborn GCs (class 3: seven slices, seven mice; class 4: ten slices, nine mice; class 5: nine slices, seven mice). (C) Variance-mean current relationship from peak-scaled non-stationary fluctuation analysis. Gray line shows a parabolic relationship. (D) Estimated single open channel conductance for AMPARs. Fluctuation analysis did not show any significant change in AMPAR channel conductance during maturation (class 3: seven slices, seven mice; class 4: twelve slices, eleven mice; class 5: nine slices, seven mice).